Archive for the ‘Neurological’ Category

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Fresh scents, toxic secrets

February 9, 2009

[Fresh scents, toxic secrets - this should come as no surprise, but, again, it's good to have the scientific validation. Whatever could have made us think that covering up the odors of normal living with artificial chemicals was a good thing? Umm, I guess that would be millions of dollars in advertising by the chemical industry, laying a guilt trip on housekeepers: "better living through chemistry"... for the industry, that is. Note: for the original research, published by kind permission of the author, please go to our Chemical Research page. ]

Fresh scent may hide toxic secret

Innocuous-sounding ‘perfume’ in detergents, air fresheners made with dangerous chemicals

Wednesday, July 23, 2008

By LISA STIFFLER
P-I REPORTER

The scented fabric sheet makes your shirts and socks smell flowery fresh and clean. That plug-in air freshener fills your home with inviting fragrances of apple and cinnamon or a country garden.

But those common household items are potentially exposing your family and friends to dangerous chemicals, a University of Washington study has found.

Trouble is, you have no way of knowing it. Manufacturers of detergents, laundry sheets and air fresheners aren’t required to list all of their ingredients on their labels — or anywhere else. Laws protecting people from indoor air pollution from consumer products are limited.

When UW engineering professor Anne Steinemann analyzed of some of these popular items, she found 100 different volatile organic compounds measuring 300 parts per billion or more — some of which can be cancerous or cause harm to respiratory, reproductive, neurological and other organ systems.

Some of the chemicals are categorized as hazardous or toxic by federal regulatory agencies. But the labels tell a different story, naming only innocuous-sounding “perfume” or “biodegradable” contents.

“Consumers are breathing these chemicals,” she said. “No one is doing anything about it.”

Industry representatives say that isn’t so.

“Dr. Steinemann’s statement is misleading and disingenuous,” said Chris Cathcart, president of the Washington, D.C.-based Consumer Specialty Products Association, in a statement.

“Air fresheners, laundry products and other consumer specialty products are regulated under the Federal Hazardous Substances Act and subsequently have strict labeling requirements,” he said. “Companies producing products that are regulated under FHSA must name on the product label each component that contributes to the hazard.”

Table

Millions are spent annually to ensure that fragrances in the products are safe, according to a joint statement from the Fragrance Materials Association, which represents fragrance manufacturers, and the Research Institute for Fragrance Materials, which works closely with the association.

Ingredients are routinely tested, and chemicals that are considered dangerous are present at levels much too low to cause harm, according to the groups.

But there are numerous reports of people — particularly those with asthma, chemical sensitivities and allergies — having strong adverse reactions, researchers said.

That’s a problem when public restrooms in restaurants or airplanes use air fresheners, or when hotels wash towels and sheets in scented laundry supplies. And even when the concentrations are low in individual products, people are exposed to multiple sources on a daily basis.

Aileen Gagney, Asthma and Environmental Health Program manager with the American Lung Association in Seattle, herself an asthma sufferer, has a rule of thumb to help avoid exposure: “If it smells bad, it’s bad; if it smells good, it’s bad.”

But even that won’t always work.

According to Steinemann, even products labeled “unscented” sometimes contain a fragrance and a “masking” fragrance to make them odor-free.

People, Puget Sound at risk?

For Steinemann’s research, published Wednesday in Environmental Impact Assessment Review, she selected a top-selling item from six categories of products: dryer sheets, fabric softeners, detergents, and solid, spray and plug-in air fresheners.

Then she contracted with a lab to test the air around the items to identify the chemicals people could be breathing.

Ten of the 100 volatile organic compounds identified qualified under federal rules as toxic or hazardous, and three of those — 1,4-dioxane, acetaldehyde and chloromethane — are “hazardous air pollutants” considered unsafe to breathe at any concentration, according to the study.

The labels gave no indication that the irritating and potentially dangerous chemicals were present, so Steinemann checked the product’s Material Safety Data Sheets. These technical documents provide ingredient information for the safety of workers and emergency responders. They, too, disclosed little detail, mostly citing ingredients such as “essential oils” and “organic perfume.”

“It’s a reasonable expectation to think that laundry products and air fresheners would be free of chemicals that can cause cancer,” said Erika Schreder, a staff scientist with the Washington Toxics Coalition.

“But as this UW study shows, it’s disturbingly easy to find toxic chemicals in everyday products like these because companies don’t have to say what’s in their products.”

Cathcart, of the Consumer Specialty Products Association, said the information’s not on the package because the “chemicals are not present in the products at levels deemed hazardous under the law. Given the limited space on product labels, it is important to include the relevant information consumers need to make intelligent use, storage and disposal decisions.”

The threat isn’t limited to people. Steinemann and others worry that the chemicals in consumer products flow from homes to the outdoors.

“These chemicals get into our water systems and into Puget Sound,” she said. They are “extraordinarily hard to get out of the environment.”

Steinemann’s research was paid for using discretionary money awarded to her as a UW professor; she wanted to avoid any appearance of a conflict of interest. She has also submitted for publication a study that goes further to examine ingredients in cleaning and personal-care products.

Regulatory gaps

With fears growing over chemicals in consumer products — lead in toys, bisphenol A in plastic baby bottles, phthalates in shower curtains and cosmetics — environmentalists and health advocates are calling for stricter regulations of chemicals in everyday goods. They also want shoppers to have more readily accessible information.

Manufacturers and trade groups representing consumer products routinely counter that there’s plenty of testing and oversight from within the industries and from government regulations to ensure safety.

In the fragranced-products arena, they point to industry Web sites with information on product ingredients and suggest contacting companies with specific questions.

Critics maintain that’s not enough.

“There’s obviously a loophole,” said Michael Robinson-Dorn, a UW law professor who aided Steinemann’s research. “We regulate many of these chemicals in other circumstances, yet when they’re in products that we’re in contact with daily, in some cases, we don’t wind up finding out about them.”

He said the items can slip between regulatory cracks by falling into the jurisdiction of multiple government agencies, none taking ownership.

“Any time you have a product that is regulated by many different agencies, it’s easy for them not to react,” he said.

In the absence of strong laws, the marketplace is starting to regulate itself.

After the Natural Resources Defense Council last fall found troubling levels of phthalates — plasticizing chemicals that can potentially harm developing babies — in air fresheners, Walgreens pulled the products from its shelves.

Last month, NRDC and other environmental groups sued the Environmental Protection Agency to force manufacturers to test air freshener safety and label products with a full ingredient list.

Steinemann’s study could push the process along.

“Consumer demand for less-toxic products will encourage companies to reformulate their products,” she said. “This is a case where a little information could have a great public benefit.”

Details on chemical risks

http://seattlepi.nwsource.com/local/371779_toxicfragrance23.html

P-I reporter Lisa Stiffler can be reached at 206-448-8042 or lisastiffler@seattlepi.com. Read her blog on the environment at datelineearth.com.

© 1998-2008 Seattle Post-Intelligencer

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The Federal Government on Printer Inks & Cosmetics (Canada)

February 9, 2009

Next, federal government will weigh in on safety of printer inks, cosmetics

Last Updated: Monday, August 18, 2008 |
CBC News
http://www.cbc.ca/consumer/story/2008/08/18/f-health-chemicals-batch3.html

The federal government is expected to release a draft assessment on Saturday of chemicals that includes a pigment used in some printer cartridges, a colouring agent used in cosmetics, and a dye used in detergents and cleaners.

The review is part of the government’s Chemical Management Plan, in which 200 chemicals are assessed in batches. The program, run by Environment Canada and Health Canada, was announced on Dec. 8, 2006.

It was under the same program that Health Minister Tony Clement announced a ban on April 18 of the import and sale of polycarbonate baby bottles containing bisphenol A. Clement said the chemical could affect early development in infants and newborns.

Studies in peer-reviewed journals had indicated that even at low doses, the chemical can increase breast and ovarian cancer-cell growth and the growth of some prostate cancer cells in animals.

The plastics industry vigorously defended the safety of the chemical, noting it has been used in a range of products for 50 years.

The U.S. Food and Drug Administration recently said the chemical was safe to use in food containers, as only trace amounts of bisphenol were found to leach into the food. Critics suggested the federal agency relied on industry-funded studies in its evaluation.

The following chemicals, included in Batch 3, are not believed to pose any risks to human health but may pose harm to the environment in low concentrations:

Disperse Red 86 is used in some textile products and Disperse Violet 57 is used to colour certain plastics.

Pigment Red 3 is used in printing inks and cartridges, paints, adhesives, wallpapers, linoleum, carbon papers, typewriter ribbons, artists’ materials and grout products.

Pigment Orange 5 is synthetic colorant used in paints, coatings, adhesives and inks.

Pigment Red 4 is a synthetic organic pigment. Environment Canada notes information on use of the chemical is confidential.

Disperse Blue 19 is used in the manufacturing of products including oils, waxes, greases, fats, emulsions and pesticide products.

Pigment Orange 2 is used to colour plastics and inks.

Pigment Red 6 can be found in chemical products including solvents, carriers, strippers and etchers.

Pigment Red 5 is used as a colorant in cosmetic goods, stationary, wood stains, paints, varnishes, latex and synthetic fibres.

Acid Blue 127, a synthetic dye, is used in soap and cleaning products.

Disperse Blue 77 is a man-made organic dye that can be found to make textile fabrics.

PBMBDP is used to make synthetic rubber for hoses, rubber seals and gaskets.

PDDAM, an organic colorant, is used to manufacture pigment, stain, dye and ink.

Acid Violet 48 is used as a dye to colour detergents and cleaners and is used to manufacture textiles.

Pigment Red 251 is used as a colorant in printing ink, pesticides, fuel additives, lubricants, paints, lacquers and construction materials.

Batch 3 also includes these chemicals which are being evaluated for their effect on unborn offspring as well as the environment:

2-Methoxyethanol acetate is used in products including paints, lacquers, glues, adhesives, waxes, oils, textile printing, film, nail polish and dry cleaning products.

2-ethoxyethanol acetate is used as a solvent in paints, varnishes, silkscreen printing inks, wood stain and leather finishing dyes.

2-(2-Methoxyethoxy)ethanol, a synthetic organic chemical, is used in a wide range of products including stamp pads, ball point and felt tip pens, hydraulic brake fluids, wood stains, household and commercial cleaners and cosmetics.

2-Methoxy-1-propanol is used as a solvent or agent in coatings, sealants, adhesives, agricultural pesticides, various types of inks, hydraulic brake fluids and lubricants, and household and industrial cleaners.

Environment Canada and Health Canada are expected to release its draft assessment of Batch 4 chemicals which include an antimicrobial used in some shampoos and deodorants and an organic compound used in certain toiletries on Nov. 15.

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Your own personal neurotoxins

February 9, 2009

Quotes:

“Everyday household things could be doing our kids harm and we don’t even really understand what they can do yet.”

“It seems like these things are in everything.”

Study: Neurotoxin In Everyday Household Items

Reporting: John Lauritsen (WCCO)
Sep 6, 2008 10:45 pm US/Central
http://wcco.com/local/neurotoxin.household.items.2.811758.html

A Minneapolis mom recently learned that ordinary, household items are contaminating her family.

“Everyday household things could be doing our kids harm and we don’t even really understand what they can do yet,” said mother Christi Williams.

Williams thought she had provided her children with a comfortable, safe living environment, but now she’s not so sure. She and her daughter Lauren recently took part in a nationwide investigation that tested for neurotoxins in children and their mothers.

The Environmental Working Group investigation focused on chemical fire retardants that are put in carpet, furniture, pajamas, rain boots and soft plastic toys. The results showed that Lauren had five times more neurotoxins in her blood than her mother. That was the most of any child in the study.

“That’s huge to me because they do all their — all the governmental regulations are based on adults. And if she has five times the levels in her system, what does that mean for, what it is doing to her?” said Williams.

Studies show that high levels of a fire retardant called Deca have caused permanent changes to behavior in mice. Kids ingest more of these chemicals because they are closer to the carpet and often put toys and other objects in their mouths.

“It seems like these things are in everything,” said Williams.

That is the challenge she and her family our now facing. The results of the investigation shocked them, but they are not entirely sure what they can do to make it better.

“People want to be protected from being set on fire, but what does that mean then for what chances you are taking with your family?” said Williams.

The fire retardant Deca is banned in Europe, but is unregulated by the U.S. Environmental Protection Agency. Some of the neurotoxins that were targeted in this study can stay in a child’s system for as long as four years.

Williams and Lauren were the only Minnesota family in the study. Out of the 20 families tested, only one parent had chemicals higher than their children.

Williams and her family have changed their diet since the investigation. They have started eating more organic foods, but Williams said it is hard to get rid of the carpet, couch, and other necessities. She is hoping for stronger, government regulations in the near future.

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BPA and your brain

February 9, 2009

BPA Impairs Synapses Formation in Brain, New Study Finds

September 03, 2008 – News Release

http://www.uoguelph.ca/news/2008/09/bpa_impairs_syn.html

The controversial chemical Bisphenol A commonly found in hard plastic food and drink containers may impair the brain’s ability to learn and remember according to a groundbreaking study conducted by researchers at the University of Guelph and Yale University.

The study reveals that continuous low doses of Bisphenol A (BPA) hinders the formation of synapses in the brain, which allow neurons to communicate with one another and are critical to the way we interpret and remember experiences.

“It dramatically impairs the formation of synapses in the regions of the brain important to learning,” said biomedical science professor Neil MacLusky. “These findings are worrisome because BPA is one of the most widely-used chemicals in the world.”

BPA is used in plastic water bottles and some baby bottles, dental prostheses and sealants, and in the lining inside of food cans. It has been proven that this chemical can leach from these products and be absorbed through human consumption.

Although previous research has been done on the harmful effects of BPA, MacLusky’s study, set to be published this week in the Proceedings of the National Academy of Sciences, is the first to mimic continuous environmental exposure levels.

Using the dose level declared safe by the United States Environmental Protection Agency for daily consumption by humans, the researchers exposed African Green monkeys living on the Island of St. Kitts to BPA for a month.

Results showed that even at this low dose BPA turns off increases in synapses density in the brain normally induced by estrogen, said MacLusky.

“Estrogen is more than just a female reproductive hormone. It enhances the rate at which some types of synapses are formed and is vital in maintaining normal neuronal structure in regions of the brain that control learning, memory and mood state. When we have BPA in our systems, it seriously impairs this process.”

Although further research is needed, these results support the possibility that BPA may be involved in human neurological conditions such as Alzheimer’s disease, depression and schizophrenia, which all feature aberrant synapse formation and are also sensitive to sex hormone levels, he said.

This study was funded by the United States National Institute of Health and the Natural Sciences and Engineering Research Council of Canada.

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“Toxins, Brain Chemistry, and Behavior”

February 9, 2009

Toxins, Brain Chemistry, and Behavior
http://www.dartmouth.edu/~rmasters/tbcba.htm

ROGER D. MASTERS
Research Professor
Dartmouth College
Hanover, New Hampshire 03755

I. The Problem

During the last two decades, evidence has accumulated that the interaction of environmental pollution, poor diet, and lifestyle contributes to the exceptionally high rates of violent crime in many American cities. Lead intoxication, even at low levels, correlates with aggressive behavior as well as learning disabilities. Manganese, a toxin that at high levels of exposure contributes to Parkinsonism, has also been linked to violent behavior. Effects of lead and manganese interact, moreover, so that individuals exposed to both show stronger effects than those exposed to either one alone. Alcohol and drug use, often associated with violent crime, increase the deleterious effects of toxic metals through complex biochemical interactions at the cellular level. These chemicals compromise the serotonin, dopamine, and other neurotransmitter systems that are integral to self-control due to their effects in lowering thresholds for violent behavior.

Environmental pollution does not impact everyone equally. Brain cells absorb toxic metals when diets are low in calcium, iron, zinc, Vitamin D, and other essential nutrients. Prenatal exposure to lead and alcohol can result in premature or low weight births, small head circumferences and learning or behavioral deficits. Bottle-feeding with commercial formulas exposes infants to four or five times as much manganese uptake as breast milk, a finding that suggests why studies show breast fed infants have IQ scores 2 to 8 points higher than comparable babies fed infant formula. In addition to direct effects of poor diet on children’s behavior, nutritional deficits thus probably combine with exposure to toxic metals to increase the likelihood of attention deficit disorder (ADD), hyperactivity, and other learning deficits. In addition, because the problems of poverty and broken families often co-vary with inadequate diet, housing with lead paint, and aging water systems, as well as inadequate prenatal health care, high rates of bottle feeding, and exposure to industrial pollution, poor urban populations are at risk for neurotoxicity in multiple ways.

The neurotoxicity hypothesis is strongly grounded in findings from a number of laboratory studies and observations of human behavior. In seven different groups of prison inmates, violent criminals had substantially higher levels of lead or manganese in their hair than nonviolent criminals or law-abiding controls. Otherwise puzzling geographical differences in rates of violent crime in the U.S. are highly correlated with environmental pollution and death rates from alcoholism. Counties in which the EPA did not report industrial releases of either lead or manganese, and where alcoholism was lower than average, had a rate of 228 violent crimes per 100,000 people (well under the national average). In contrast, counties with industrial releases of lead and manganese and higher than average alcoholism had rates of violent crime of 969 per 100,000 (three times above the national average). (The statistics linking differences in the rate of violent crime to lead, to manganese, and to alcoholism would each occur by chance less than once per 10,000 times.) Controlling for 17 other factors, including population density, poverty, and ethnic composition, the three sources of neurotoxicity are significantly associated with violent crime.

II. Current Research

With the support of a grant from the Environmental Protection Agency, current work is exploring a number of ways that toxic pollution affects the public. Data from a number of surveys of children’s blood lead are being combined with socio-economic and demographic data from the U.S. Census Bureau, health data from the Center of Disease Control, pollution data from the EPA, and crime data from the FBI. Our research will focus on the extent to which lead is being absorbed by humans due to: a) water treatment procedures; b) industrial releases of lead and other toxins; c) plumbing systems, leaded paint, and other sources of lead associated with old housing; d) other sources, such as lead residues in soil, that are particularly common in the center of some American cities; and e) dietary habits (such as shortages of calcium and iron) and demographic factors (such as poverty, stress, and minority ethnicity) which are known to be associated with increased risk of lead uptake. The resulting geographical variations in lead levels in children’s blood will also be studied as a factor that might explain rates of crime, educational failure and disease that are unusually high.

We are also studying “risk co-factors” that make lead and other toxic metals in the environment more dangerous to local residents. Here our emphasis will be on the use of silicofluorides as agents in water treatment. There are two reasons for this focus. First, both fluosilicic acid and sodium silicofluoride are toxins — and both leave potentially toxic residues if they do not dissociate completely. In studying the correlations between the use of these chemicals and crime, disease, and behavioral dysfunction, we seek to establish clearly whether or not these compounds are poisoning the public. Second, the silicofluorides apparently function to increase the cellular uptake of lead and other toxic metals, such as manganese; confirming correlations between silicofluorides and lead uptake should thus clarify the extent to which these compounds are risk co-factors for toxicity and other hazardous effects.

III. Results to date.

Our analysis of data from Massachusetts has revealed several important findings which are confirmed, where evidence is available, by preliminary analyses of the 129 cities covered in the September 1992 EPA News Release and of county data in West Virginia.

1. Communities with a higher percentage of children having blood lead over 10 mg/dL are significantly more likely to have higher rates of violent crime and higher rates of educational failure.

2. Communities using either fluosilicic acid (H2SiF6) or sodium silicofluoride (NaSiF6) have significantly higher rates of crime than those using sodium fluoride or delivering unfluoridated water (with the exception of towns with naturally fluoridated water).

3. The use of fluosilicic acid (H2SiF6) to fluoridate public water supplies significantly increases the amounts of lead in the water (whereas the use of sodium silicofluoride (NaSiF6) or sodium fluoride (NaF) does not.

4. There is no linear relationship between the amount of lead in a community’s public water supply (as measured by current methods of determining “90th percentile first draw water lead”) and the rates of violent or property crime.

IV. Implications

If these research hypotheses are confirmed, it should be possible to target both criminal and civil environmental enforcement strategies in a way that produces major public health benefits by reducing exposure and absorption of lead pollution and thereby reducing violent crime, learning disorders. and such diseases as hypertension. In the past, questions have been raised about the need to regulate industrial releases of lead and some have doubted that chronic exposure to low levels of lead pollution actually harm humans. Other efforts, such as the removal of leaded paint from old houses, have also been subjected to criticism on the grounds that they actually release more lead into the environment. If the hypotheses tested in this study are confirmed, efforts to remove lead from the environment will be validated and their effectiveness improved. In addition, this study may also suggest some relatively inexpensive non-enforcement interventions, such as ending or modifying water fluoridation procedures using silicofluorides. For all these reasons, environmental protection will be greatly enhanced by the acquisition of more comprehensive evidence of how environmental sources of lead and the risk co-factors for lead uptake are correlated with disease, crime, and behavioral dysfunction. The neurotoxicity hypothesis implies the benefits of a biomedical and dietary approach to educational failure, crime, and social deviance. Studies show IQ increases of as much as 15 points among children with poor diets who are given vitamin supplements. Removal of lead (“chelation”) and other methods of biochemical normalization have also been found to improve behavior and learning. Other studies indicate that the successes of Head Start are due in good part to its nutritional component. Because many children do not continue to benefit from balanced diets after Head Start, poor nutrition may explain the frequently observed declines in educational performance after these programs have been completed. Interventions such as good neonatal care, breast-feeding, vitamin supplements, and school lunches might therefore improve educational performance, as well as reduce violence and social disintegration.

The neurotoxicity hypothesis provides a new and potentially crucial dimension to accepted theories of crime. Factors like poverty, population density, social disintegration, race, easy access to guns, and violence on TV are obviously important contributors to violence, yet they do not effect everyone the same way. Studies of the behavioral impact of heavy metals can increase our knowledge of why these factors influence some individuals more than others. Crime prevention, better systems for screening prison inmates for potential violence, and cost-effective parole or probation options are all attractive. At the same time, the implications of the neurotoxicity hypothesis for our social, education, and legal systems are enormous. This approach does not excuse crime on the grounds of biochemistry. If poor diet and alcoholism contribute to learning disabilities and crime, this information ought to have the same status as knowing that drinking and driving do not mix. Given advances in neuroscience, dare we ignore the behavioral effects of neurotoxicity when this knowledge promises more effective crime prevention — and perhaps also more effective rehabilitation — than current methods?

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Pesticides and the brain

February 7, 2009

[Important for its focus on developing brains: "neuro-developmental toxicity".
Quotes: "pesticide chemicals that could be damaging included organophosphates, carbamates, pyrethroids, ethylenebisdithiocarbamates and chlorophenoxy herbicides."
"More than 25 percent of fruits, vegetables, and cereals contain detectable residues of at least two pesticides."]

From: Alister Doyle, Environment Correspondent
Published October 24, 2008

Many pesticides in EU may damage human brain: study

OSLO (Reuters) – Many pesticides used in the European Union may damage brain growth in fetuses and young children, according to a study published on Friday.

The study urged the European Union to tighten restrictions.

“Toxicity to the brain is not routinely included in testing pesticides,” Philippe Grandjean of the Havard School of Public Health and the University of Southern Denmark told Reuters.

“Because many of them are by design toxic to the brain of insects, it is very likely that they are also toxic to human brains,” he said of a review of almost 200 scientific reports worldwide about the brain and pesticides.

“Laboratory experimental studies using model compounds suggest that many pesticides currently used in Europe…can cause neuro-developmental toxicity,” Grandjean and two colleagues in Denmark wrote in the journal Environmental Health.

The developing brain of the fetus and young child is far more sensitive than the adult brain to disruptions from chemicals, they said.

The study focused on the use of pesticides in the 27-nation EU, which is currently reviewing pesticide laws. It urged greater testing and caution in approving chemicals because of uncertainties about their effects.

Manufacturers say their pesticides are safe for humans.

“Many other countries are watching what the EU is doing…It should take these matters much more seriously than in the past,” Grandjean said. Many pesticides used in the EU are also used in other nations.

Pesticides used on food crops in the EU exceed 140,000 tonnes a year, corresponding to 280 grams (10 ounces) per EU citizen, the study said.

More than 25 percent of fruits, vegetables, and cereals contain detectable residues of at least two pesticides.

The study said that pesticide chemicals that could be damaging included organophosphates, carbamates, pyrethroids, ethylenebisdithiocarbamates and chlorophenoxy herbicides.

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Chemical Overload

February 7, 2009

We’re in chemical overload
Viviane Maraghi expected the blood tests to show she would have some chemical pollution in her body, but nothing like this.

Story by WILLIAM MARSDEN
The Gazette

Saturday, June 21, 2008

After all, she viewed herself as “very environmentalist,” carefully monitoring what she ate and and the household products and items she purchased.

Nevertheless, lead, arsenic, mercury, PCBs, PBDEs (a flame retardant banned in Europe and eight U.S. states but still in use in Canada), plus an array of other chemicals that have been linked to cancer, birth defects and neurological diseases were all well represented in her bloodstream.

Her blood tested positive for 36 of 68 potentially toxic chemicals, many of which never actually leave the body, but continue to accumulate over time in tissues such as fat or bone.

They get there because they are in the air we breathe, the water we drink, the food we eat and the products we use.

Over the last 50 years, from 70,000 to 100,000 different chemicals have been introduced into the world’s markets with about 1,500 new ones added each year. They are found mostly in industrial processes and consumer products such as cosmetics, cleaners, food, plastics and more recently the circuit boards that run our computer electronics. Even a seemingly innocuous polyvinyl chloride (PVC ) shower curtain contains up to 108 toxic chemicals – some of which have already been banned by some countries, but not in Canada.

Manufacturers often argue that these chemicals have been used for decades with no reported incidents of harm. But who has ever been able to say: “I’m dying of cancer and it’s the shower curtain’s fault?” Fact is, only sporadic toxicity studies have been done on the enormous array of industrial chemicals used in Canada.

Only now are governments beginning to examine the dangers posed to human health and ecosystems. Many western governments are initiating new chemical controls as part of an international Strategic Approach to International Chemical Management agreement signed in Dubai in 2006. The agreement was sparked by the realization that nearly every square inch of the planet is now contaminated to one degree or another with a chemical pollutant. What’s more, over the next 15 years, chemical production is expected to climb 80 per cent. The main goal is to assure that by 2020 everybody uses chemicals safely.

Leading the way is the European Union with a new program called REACH (Regulation on Registration, Evaluation, Authorization and Restriction of Chemicals) that requires industry to prove the safety of their chemicals and consumer products before they reach the market.

The next 10 years will see a vast number of chemical assessments, all of which will be made public, that will shed light on the murky world of chemical toxicity. It’s a world that until now has remained hushed up or simply ignored.

The ultimate result could be a sea change in how we develop products for the consumer market. It could lead to widespread bans on some substances, which might see many consumer products disappear from the shelves or be replaced with safer equivalents.

It is an issue that is becoming increasingly important worldwide as species disappear, health costs sore, and concern grows that many diseases, particularly cancers and autoimmune diseases, might be the result of chemical pollution.

Few tests have been performed on Canadians to pinpoint and quantify the chemical pollutants accumulating in our bodies. But that is beginning to change.

Health Canada is testing 5,000 Canadians for chemical contamination and preliminary results should be available in November.

The tests done on Maraghi, 35, and her son Aladin, 12, in 2005 were part of a research project called Toxic Nation undertaken by the Toronto-based activist group Environmental Defence.

An attempt to wake up Canadians to the growing danger of chemical toxins entering our bodies, the study tested 11 individual volunteers plus five families.

Maraghi and her son took part, she said, because she was eager to help raise Canadian’s awareness of the dangers posed by the millions of kilograms of chemicals emitted into the environment each year.

Each volunteer had high levels of many different chemical pollutants in their bloodstreams.

Even Maraghi’s son Aladin, who was only 10 when the tests were performed, tested positive for 25 chemicals and had higher lead levels than his mother.

Both had high levels of organophosphate insecticides, probably because they spent three years living in the country, Maraghi said.

“It was surprising to us because we are very aware and a big part of what we eat is organic, and we try to be careful with the types of products we use in the house,” she said. “So my first reaction was, ‘what happens with people that don’t take care of that and are not aware?’ ” To date, consumers have been unsuspecting lab rats for chemical companies who have been allowed to market their products without ensuring they won’t damage human health or the environment. Bans have been imposed only after the damage is done.

So far, preliminary studies in Europe and the United States strongly indicate we all are contaminated.

A recent U.S. study found most of its subjects had rocket fuel chemicals in their bodies as well as a host of other toxins like bisphenol A, which gives the clear, pliable strength to plastic water bottles as well as baby formula bottles. Health Canada tests reveal that it disrupts the body’s hormones and could be toxic even at low levels. Because the government here is worried that bisphenol A migrates into baby formula, Health Canada is considering a ban on its use in baby bottles.

Canada, however, is still far behind the EU in assessing chemicals.

The EU’s REACH program officially began on June 1, when it required that every company register chemicals sold in the EU, in bulk or in consumer products. Companies must reveal the chemical composition and toxicity of their consumer products and must finance their own toxicity studies. All of this information will be entered into a public registry. Essentially, until a company proves the safety of its product, it cannot be sold in the EU.

The EU hopes the REACH program will motivate companies throughout the world to produce safer products. Given the enormity of the EU market (it has surpassed the U.S.), the motivation to conform will be considerable.

Canadian exports to the EU, for example, have increased 600 per cent since 1998, totalling $4.7 billion last year. Only a small percentage of our total chemical exports go to the EU (most go to the U.S.), but it is not a market Canadians would want to lose.

While public health and a safe environment for all species are the priorities of the REACH program, EU officials also note that the high costs of cleaning up contaminated sites as well as fighting diseases caused by chemical contamination are significant reasons to implement the program.

The EU says the program will cost industry up to $8.2 billion over the first 11 to 15 years. However, it estimates a reduction of .01 per cent in the overall burden of disease would save about $80 billion over 30 years.

A wide array of studies indicate a significant proportion of disease is directly related to environmental and occupational factors like chemical contamination. The World Health Organization estimates that the poor, particularly children and women, suffer disproportionately from diseases that are related to environmental contamination. In developing countries, up to 35 per cent of diseases are caused by contaminated environments.

The figures could, however, be much higher for all societies. But because few studies have examined this issue, nobody really knows. The studies that have been done indicate serious problems.

For example, scientists at Université Laval have revealed that Inuit children and their mothers in northern Quebec have high levels of organochlorines such as PCBs and the extremely toxic chemical dioxin. These chemicals can damage the immune system, especially as it develops in the womb and during infancy. This might explain why Inuit children have been found to have a much higher incidence of acute infections such as ear and lung infections compared with people living in southern Quebec. Most of the chemical pollution in the North has been brought from the South by ocean currents that circle the Arctic. The contaminants concentrate at the top of the food chain in predatory fish and mammals, which are the main food source for the Inuit.

In some cases, studies show that Inuit children’s immune systems have been so badly damaged that doctors are hesitant to prescribe antibiotics for fear they will worsen the infection.

Canada has started its own chemical assessment program. Unlike the EU program, which demands that industry foot the bill for toxicity assessments, the Canadian program is completely financed by the taxpayer.

“On the level of depth and breadth of coverage, the REACH program wins on both accounts,” John Margeson, Industry Canada’s chemical specialist, said.

Canada’s umbrella law for the regulation of chemicals is the Canadian Environmental Protection Act (CEPA).

Under this law, which was passed in 1999, all new chemicals produced in or imported into Canada since 1994 have to be assessed for health and environmental effects by Health Canada.

However, companies can market a chemical before tests are completed. Essentially, it is up to the government to prove the chemical is a risk before it is taken off the market.

There is also no obligation for the government to keep a dangerous chemical off the shelves. The law gives the government up to two years after assessing a chemical to take action, but does not oblige it to ban a dangerous chemical.

“These chemicals are in all kinds of different products and it’s going to be very interesting to see how much political will there is and whether they have the guts to do things that are going to be disruptive to the market,” Dr. Kapil Khatter, pollution policy advisor for Environmental Defence, said. “It’s hard not to bow to the social and economic pressures.” What’s more, when the new CEPA was made law in 1999, it did not require that companies supply toxicity reports for the 23,000 chemicals already widely used Canada.

It did, however, obligate the government to sort the chemicals into those that are inherently toxic to humans or to the environment.

The sorting process was finally completed in September 2006. The government identified more than 4,000 chemicals, which it decided required further study. Of these, it labelled 200 “high priority.” Of these 200, 66 are potentially dangerous to human health and the rest pose ecological dangers. All of them have remained on the market as the government completes its assessment. The final test results for the first 15 chemicals will be published July 5. But that is nowhere near the end of the assessments.

Christine Norman, acting director of the risk and impact assessment branch of the program, said it will take two more years to complete the testing on the 200 high-priority chemicals. Then there are another 2,600 chemicals from the petroleum sector that will have to be assessed; another 1,400 are considered of medium priority. How long that will take is not clear.

So far, Health Canada has identified 16 substances that pose a high risk to humans and another 17 that are toxic to other species.

One of those substances is thiourea, which is used in metal finishing solutions as well as silver polish, tarnish removers, metal cleaners and in the manufacture of pharmaceuticals and in the pulp and paper industry.

The federal government claims that in 2006, industry imported between 10,000 and 100,000 kilograms of thiourea. Norman said the government knows the exact number but won’t make it public because industry insists it is a business secret.

Importation was permitted despite the fact that dozens of studies dating back as early as 1947 showed that even at low doses rats and mice fed thiourea developed a variety of cancerous tumours. It can enter the human body orally, through inhalation or through skin contact.

The Chemical Substances Program published an assessment of thiourea on May 8 stating that it could cause cancer “at any level of exposure.” The report said thiourea should be considered a “substance that may be entering the environment in a quantity or concentration or under conditions that constitute or may constitute a danger in Canada to human life or health.” But despite its potential danger to humans, the chemical is still widely used in Canada.

Norman said the final assessment is still months away. She said two years after the final assessment, Health Canada will publish a risk-management assessment that will outline steps the government should take to deal with the dangers. These could include an outright or limited ban on its use, or simply a warning on packages.

The chemical bisphenol A is another example of the slow pace of government action. Global production, now more than three billion kilograms per year, is increasing. Bisphenol A has been found in high concentrations in municipal and industrial wastewaters, sludge and biosolids, which are often spread as fertilizer. As well as a danger to humans, “bisphenol A is acutely toxic to aquatic organisms and is considered highly hazardous to the aquatic environment,” Health Canada states in its assessment. Yet the government is only considering a ban on its use in baby bottles, without considering its danger to wildlife or the broader Canadian population.

Khatter said the government just wants to give the appearance of taking action. “There is an intellectual gap between the people who wrote the risk assessment and the minister’s office,” he said. “The risk assessment says this stuff is really toxic to aquatic wildlife at very low levels and we have to do something about releases to the environment, period, but all the government seems to do is ban it from baby bottles.” In March 2007, Health Canada began testing 5,000 Canadians for the chemical pollution in their bodies. Tests are being done on blood, urine, hair, saliva and breast milk.

The idea is to track chemical contamination levels in a broad spectrum of the population and measure trends in exposure over time and by geographical region.

Eventually, Health Canada hopes to be able to compare the medical records with the level of chemical exposure to find a possible relationship between the two.

Statistics Canada is compiling the data. Jeanine Bustros, director of the project, said they have already completed about two thirds of the testing including subjects in Montreal and the south shore communities.

Preliminary results for heavy metals like cadmium, lead and mercury are scheduled to be made public in November. Final results for all 5,000 participants across Canada will be released January 2010, she said.

Each participant fills out a lengthy and detailed health and lifestyle survey detailing such data as illnesses, daily routines, exercise regiments, food consumption, job environment, beauty products, hobbies, stress levels and products used in the home.

“This is the first time we will have normative data on the level of chemicals in the Canadian population,” she said. “This means that we will have a point of reference to compare, say, the levels of lead in a person with the norm.” Advances in the technology of detection are making it easier for scientists to detect the present of even the smallest quantities of chemical pollutants. We can now detect chemical levels in parts per trillion.

“One part per trillion is one second in 32,000 years,” Dr. Joe Schwartz, a chemist at McGill University’s science and society department, noted. “That you can detect things in that concentration is far better than finding a needle in a haystack. It’s like finding a needle in a world full of haystacks.” Our ability to measure data, however, has outstripped our ability to interpret the data, he said. The ultimate goal has to be to find out what, if any, detrimental health or environmental effects exist. With many chemicals, this is still a black hole.

Most studies that detect potentially dangerous toxins are the result of giving large doses to rats, but what kills a rat may not have any effect on humans.

“The value of bio-monitoring is going to be long term,” Schwartz said. “If we have a good baseline now, we get good data and then we check 10, 20 years down the road to see if there is any alteration in disease patterns for those people and then you look back to see if there is any link.” So while Maraghi and her son Aladin may know the chemicals that are polluting their bodies, finding out the impact is a wait-and-see game.

She said her son never gets sick. She on the other hand is plagued with migraines.

“I have had them since I was young. But it’s hard to relate it to anything.” But just knowing about the chemical cocktail in her body is a good thing. It’s made her even more careful of what she buys.

“I lately brought a mattress for my son and since we were aware of the products they can put in, like the products against fire, we asked for a mattress without (fire retardants). Whereas before when I bought any of this furniture, I would never ask this question because I was not aware.”

- – -

Don’ts

1. Bathroom

Things to avoid: Cosmetics, toiletries and perfumes with synthetic fragrances (many contain phthalates and other harmful chemicals).

Anti-bacterial toothpaste, toothbrushes and mouthwashes that contain triclosan.

Vinyl shower curtains and fabric shower curtains with water-repellent coating.

2. Artist’s studio

Avoid: Painting and drawing materials that contain solvents, which may contain chemicals like toluene and xylene.

Pigments in paints that contain heavy metals, e.g., lead. Some pigments may be contaminated with PCBs and dioxins.

3. Bedroom

Avoid: Sheets that are wrinkle-resistant (they contain formaldehyde), or made with pesticide-treated cotton.

Moth-proof wool blankets (they contain pesticides).

Mattresses with brominated flame retardants, plastic, or foam.

Dry-clean only clothes (most dry cleaners use PERC).

Clothing with stain repellents, wrinkle-resistant treatments (they contain formaldehyde), brominated flame retardants, pesticide-treated cotton, or plastic labels.

Nursery

Avoid: Polycarbonate plastic feeding bottle (identifiable by the No. 7 marked on the bottom of the bottle inside a recycle symbol).

Latex rubber nipples.

PVC-containing toys or soothers.

Disposable diapers (most contain dyes, fragrances and plastics).

4. Home office

Avoid: Wood with a toxic finish; and particleboard, fibreboard, and plywood. These woods are used as sub-flooring, wall covering, and inside cabinets for shelving. Most products made of these wood types contain formaldehyde.

Computers and other electronics with brominated flame retardants.

5. Kitchen

Avoid: Vinyl floors.

Tinned food (the cans are lined with an epoxy resin that may leach bisphenol A).

Plastic food wrap (may contain bisphenol A).

PVC and polycarbonate plastic bottles, containers, etc., Nos. 3 and 7.

Microwaving food in plastic wrap.

Non-stick cookware.

Ceramic glazed cookware (may contain cadmium and lead).

Antibacterial soaps and cleaners that contain triclosan.

Cleaning products with harsh chemical ingredients and synthetic fragrances (often strengthened with phthalates).

6. Living room

Avoid: Carpets that contain stain repellents and brominated flame retardants.

Upholstery and furniture that are treated with stain repellents and brominated flame retardants.

Curtains that are treated with stain repellents and brominated flame retardants.

PVC-containing mini-blinds from Mexico or Asia might contain lead.

Chemical air fresheners.

7. Garden

Avoid: CCA pressure-treated wood for patios and fences (it has a green tint to it and leaches arsenic).

Chemical pesticides.

8. Basement

Avoid: Toxic chemicals and high-level VOCs in paints, varnishes, paint-stripping products, gasoline, glue, adhesives, and solvents.

Laundry detergents and fabric softeners with synthetic fragrances.

Chlorine bleach.

- – -

Do’s

1. Bathroom

Try these alternatives to chemical-laden products:

Products that don’t contain phthalates or toxic chemicals. The Guide to Less Toxic Products (www.lesstoxicguide.ca) lists Canadian products that are safe.

Organic cotton and unbleached sanitary pads.

Acrylic bathtubs, or refinish your porcelain one with a tub refinishing kit (available at hardware stores).

Hemp shower curtains.

2. Artist’s studio

Try these alternatives:

Mineral spirits – for thinning oil-based paints and varnishes or for general cleaning purposes.

Water-based markers.

Water-based and acrylic paints.

Note: Water-based paints may contain formaldehyde, acrylics may contain ammonia – but they are still considered safer than oil-based paints.

3. Bedroom

Try these alternatives:

Sheets that are 100-per-cent cotton, hemp, linen or wool, and preferably organic and unbleached.

Mattresses with cotton stuffing or cotton padding around the foam core. If a new mattress is not an option, wrap your mattress in an untreated 100-per-cent cotton cloth barrier sheet with a high thread count (250 or more).

Unbleached clothing made of organic cotton, hemp, linen or wool.

In the nursery:

Breast feeding is best. Next option is bottles made of glass or plastic No. 1, 2, 4 or 5.

Silicone nipples.

Non-flexible plastic, wooden, or organic, untreated cotton toys.

Organic, untreated cotton diapers and clothing.

4. Home office

Try these alternatives:

Solid wood with a non-toxic finish, metal, or used furniture (but avoid painted furniture from before 1960, it may contain lead). IKEA has made a commitment to sell products that are free from hazardous substances.

Electronics from companies that have eliminated PBDEs from their products – these include Apple, Dell, Hewlett Packard, IBM, Intel, Sony and Toshiba.

5. Kitchen

Try these alternatives:

Wooden, ceramic, marble, cork or bamboo flooring.

Aluminum foil, wax paper, food-grade reusable containers.

Glass containers, or plastics Nos. 1, 2, 4 and 5.

Glass, ceramic and plastic containers that are labelled microwave safe.

Organic food.

Cast iron and stainless steel cookware.

Fragrance-free and biodegradable products, and homemade all-purpose cleaner. The Guide to Less Toxic Products (www.lesstoxicguide.ca) lists safe products and homemade recipes.

6. Living room

Try these alternatives:

Organic or natural fibre carpets, such as wool, cotton, rattan or jute.

To freshen the air, try potpourri, baking soda, or just simply open the windows.

7. Garden

Try these alternatives:

Organic gardening methods such as hand-picking weeds, mulching and planting flowers that attract beneficial insects to feast on pests.

8. Basement

Try these alternatives:

Products that are water-based, plant-oil based, and those that have low-level VOCs. EarthEasy (www.eartheasy.com) lists non-toxic paints and paint strippers.

Biodegradable, non-chlorine liquid bleach or oxygen bleach powder.

References:

environmental defence, www.environmentaldefence.ca/

toxic nation, www.toxicnation.ca/go-toxic-free/alternatives

© The Gazette (Montreal) 2008

h1

Your Daily Dose

February 6, 2009

Several references on chemicals in our daily lives, whether we want them or not – cosmetics, detergents, plastics, scented products – many with neurotoxins, affecting human and environmental health in a variety of ways, including reproductive health.

“Canada Declares Chemicals Used in Cosmetics to be Toxics”
Quote: “The Canadian government today declared two chemicals used in lipstick and other personal care products to be toxic to the environment” [January 30, 2009]
http://www.ens-newswire.com/ens/jan2009/2009-01-30-01.asp

“Home Sick”
Book reviews in The Washington Post of Poisoned Profits: The Toxic Assault on Our Children, by Philip and Alice Shabecoff, and The Body Toxic: How the Hazardous Chemistry of Everyday Things Threatens Our Health and Well-being, by Nena Baker. Reviews by Seth Shulman.
Quotes: “The Shabecoffs deserve credit for forcefully urging the issue of our children’s environmental health onto the national agenda where it surely belongs.”
“Baker has written an illuminating, consumer-oriented book that sifts through some of the latest findings about the dangers of everyday chemicals.”
http://www.washingtonpost.com/wp-dyn/content/article/2008/09/04/AR2008090402404_pf.html
And reviews of the same books in the San Francisco Chronicle by a staff member of the San Francisco Medical Society:
http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2008/10/10/RVA813D4LD.DTL

“Neurotoxin In Everyday Household Items”
Quotes: “Everyday household things could be doing our kids harm and we don’t even really understand what they can do yet,” said mother Christi Williams.
“Many of these chemicals are linked not just to the petro-chemical industry but to the toxins that infuse our daily lives: solvents, detergents, cosmetics, herbicides, pesticides – plastics. As the Commonweal Biomonitoring Resource Center concluded in its recent study of chemical contamination: ‘much of our exposure may be from products we have assumed to be safe for use.’ “
http://wcco.com/local/neurotoxin.household.items.2.811758.html

“This toxic life”
Sarnia’s “chemical valley”, Aamjiwnaang, gender-bending, carcinogens, asthma – warning us of where we’re all headed: “where the environment is concerned we all live downstream”.
Quotes: “‘Millions of tons of reproductive toxins are spewed out by these facilities year in, year out. Their effect on animal life has been well documented throughout the Great Lakes. To think these poisons would affect everything else and not the human population is bizarre.’ ”
“Critics predict that in 10 years the fallout from the petro-chemical and plastics plague will rank with tobacco and pesticides as a major global public health issue.”
http://www.newint.org/features/2008/09/01/keynote-plastic/

“The Health Hazards of ‘Fragrances’: Toxic chemicals found in common scented laundry products, air fresheners“
Quote: “A University of Washington study of top-selling laundry products and air fresheners found the products emitted dozens of different chemicals.”
Each of the products tested gave off at least one chemical Federally classified as toxic or hazardous, yet none – repeat, none – of them listed those chemicals on their labels.
http://www.cbsnews.com/stories/2008/07/25/health/webmd/main4295506.shtml
And a link to more info on the major researcher, Dr. Anne Steinemann, http://water.washington.edu/Outreach/Events/SpecialEvents/oslsAS.html

“Essential vs Fragrance Oils: The Hazards of Scents”

Quote: “95% of the chemicals found in these oils are synthetic compounds derived from petroleum, and include chemicals such as benzene derivatives, aldehydes, and others capable of causing cancer, birth defects, central nervous system disorders (CNS) and allergic reactions. Today, fragrances are marketed to an unsuspecting public who think that these scents are natural.”
Phthalate esters, hormone disruption, neurological and respiratory effects – and if that’s not enough, waste water treatment facilities do not remove fragrance chemicals, and they have been found in our drinking water… not to mention lakes, rivers and groundwater.
http://www.hans.org/enews/issue/90#a5
http://www.herc.org/news/perfume/risks.htm
http://www.ourlittleplace.com/perfume.html

“Plasticizer related to lower hormone levels in men”
Synopsis: http://www.environmentalhealthnews.org/ehs/newscience/phthalates-and-mens-lower-hormone-levels
Quotes: “ Adult men with average amounts of phthalates in their urine had lower levels of two important hormones — testosterone and estrogen — in their blood. The hormones are necessary for normal sperm production and function.”
“This is the first study to show a relationship between phthalate levels and hormone levels in adult men.”
The original study: “Urinary Metabolites of di(2-ethylhexyl) phthalate Are Associated with Decreased Steroid Hormone Levels in Adult Men”
http://www.andrologyjournal.org/cgi/content/abstract/jandrol.108.006403v1

“Common Chemicals May Affect Fertility”
Quote: “Exposure to a type of chemical found in everyday items such as clothing, carpets, and food packaging may be adversely affecting women’s fertility, delaying the time it takes them to become pregnant, according to a new study. In the study, the higher the concentrations of these chemicals — called perfluorinated chemicals (PFCs) — in the women’s blood samples, the more likely the women were to take more than 12 months to get pregnant.”
http://www.webmd.com/infertility-and-reproduction/news/20090128/common-chemicals-may-affect-fertility?print=true
For a PDF of the study, “Maternal levels of perfluorinated chemicals and subfecundity”, go here: http://humrep.oxfordjournals.org/cgi/reprint/den490v1